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Key Points: Why Tapering Matters : Avoids rebound weight gain caused by sudden appetite increases and slow metabolism

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The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities

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In addition, GSTA4 expression levels could also predict the risk of IA in women (AUC = .87, p = .005, Figure 4C)

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1 Two other glucagon-like peptide-1 receptor agonist (GLP-1) medications, tirzepatide and liraglutide, have also been approved for weight loss by the FDA

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