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Although lowering of insulin levels with diet or drugs such as metformin and diazoxide seems generally beneficial, some practitioners also utilize strategic elevations of insulin levels in combination with chemotherapeutic drugs
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We have assessed various metabolic parameters after short and long exposure of clonal BRIN-BD11 -cells and rodent islets to the GLP-1R agonist Exendin-4 (50 nM)
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The implications extend beyond diabetes, with broad applications in oncology, neurodegenerative, and inflammatory diseases, potentially accelerating the development of new treatments
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