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Schmidt H, Taubert H, Wurl P, Bache M, Bartel F, Holzhausen HJ, et al

Notably, peptides with strong DPP-IV inhibitory activity generally consist of 28 amino acid residues, with Pro or Ala frequently occupying the second N-terminal position [165]

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Wnt ligand proteins cooperate with LRP5/LRP6 as co-receptors and a seven-transmembrane-spanning protein known as Frizzled, resulting in a complex that triggers various ubiquitination and phosphorylation effects