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(2022) ( Epub 2022/03/11 )

as such only one-third of the reference group were normotensive, with the remainder having treated hypertension

Empagliflozin had no effects on mating, fertility or early embryonic development in treated male or female rats up to the high dose of 700 mg/kg/day (approximately 155 times the 25 mg clinical dose in males and females, respectively)