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Second, any mild stimulatory effects from improved cellular energy production are more appropriate during waking hours than before bedtime

The American College of Obstetricians and Gynecologists (ACOG) Practice Bulletin on menopausal hormone therapy states: "Custom-compounded bioidentical hormones are not FDA-approved and carry the same risks as conventional hormone therapy, with the additional risk of variable potency" [11]

And it shows that patients whose prescription was for an indication of obesity alone were significantly less likely to fill their prescription than if the prescription was for both diabetes and obesity, or for diabetes alone

EC50 12.7 ng/ml (1.4 nM)