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It is lipophilic and the acidic environment of the gastrointestinal tract can deactivate it, leading to its reduced bioavailability [144]

Always consult professionals about personal use

Mechanistically, ox-LDL induces lipid peroxidation by inhibiting the SREBP-1/SCD1/FADS2-mediated lipid biosynthesis pathway, leading to endothelial damage and ultimately inducing ferroptosis (46)