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As compared to the wild-type -Thalassemia/HbE patients, the heterozygous UGT1A6*2 without UGT1A1*28 genotype exhibited a reduction in AUC of the free drug and of APAP glucuronide which might be due to UGT1A6*2 polymorphism

They demonstrated that the expression of IL-1, IL-10, and interferon gamma (IFN-) were the lowest in the high MO group, and no difference was found for IL-6, monocyte chemoattractant protein-1 (MCP-1) and TNF cytokines among the groups