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doi: 10.3389/fnmol.2021.793004 Received 11 October 2021 Accepted 29 November 2021 Published 17 December 2021 Volume 14 - 2021 Edited by Inmaculada Segura, Ludwig Maximilian University of Munich, Germany Reviewed by Jong-Woo Sohn, Korea Advanced Institute of Science and Technology, South Korea

References: Davies, M., Frch, L., Jeppesen, O

Progression of retinopathy with glucagon-like peptide-1 receptor agonists with cardiovascular benefits in type 2 diabetes: a systematic review and meta-analysis

Even though additional physicochemical properties play important roles, placental transfer of drugs with such high molecular size is generally not anticipated in the first trimester of pregnancy, unless a specific mechanism for transfer exists