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Researchers compared PQQ with the standard post-heart attack clinical treatment (metoprolol, a beta-blocker) in rats

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3.6 Ferroptosis: iron-dependent cell death Ferroptosis, a non-apoptotic form of regulated cell death involving iron ions and lipid peroxidation, is characterized primarily by the accumulation of lipid peroxides in the cell membrane (50)

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Improvements are usually seen after several weeks of therapy or topical application

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