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4.5.2 RAS, 5-HT, and stress Serotonin (5-HT) is an important neuromodulatory transmitter and decreased 5-HT production may result in mood disturbance, aggression, and other neuropsychological impairment (165)

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The expression of MOTS-c is age-dependent and has been detected in multiple tissues, including skeletal muscle, T cells and in systemic circulation 6,7,8,9,10 and the pancreas 7,11