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In that setting, patients are limited to one dose per 24 hours preferably taking a few days per week off

this could include HPLC-MS/MS approaches

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What this means for patients: the 503B large-scale pathway is effectively closing

The spectrum ranges from simple steatosis (fat accumulation without significant inflammation) to nonalcoholic steatohepatitis (NASH), which involves inflammation and hepatocyte injury that can progress to fibrosis, cirrhosis, and hepatocellular carcinoma