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Among patients who persisted with their medication one year after their initial prescriptions, the proportion who achieved 10% or more weight reduction was 61% with semaglutide for obesity, 23.1% with semaglutide for type 2 diabetes, 28.6% with liraglutide for obesity, and 12.3% with liraglutide for type 2 diabetes

These effects are often sustained over a 6- to 12-hour window following administration, offering flexibility and extended performance benefits

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A 4-week cycle works well for most people on weekly dosing: Week 1 Left abdomen Week 2 Right abdomen Week 3 Left thigh Week 4 Right thigh Repeat the cycle from Week 1 after Week 4