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However, clinical studies showed that inhibition of IGF-1R has very limited efficacy due to the development of resistance to IGF-1R blockade in tumor cells

however, the research in brain endothelium is still required to evaluate the role of Se in cell adhesion in BBB and BCB

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The important thing is knowing how to use it properly and what to expect

Contrary to our hypotheses, we observed no significant group differences in either GSH or GABA+ concentrations in any of the four brain regions of interest: SM1, Thal, mPFC, and SMA