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Competing interests VRA has served as a consultant for Applied Therapeutics, Fractyl Health, Novo Nordisk, Pfizer, and Sanofi

While direct evidence for NET-driven pathology in PCOS remains limited, mechanistic insights from related inflammatory and metabolic diseases indicate that NET-associated pathways can amplify thrombo-inflammatory signaling, endothelial dysfunction, and tissue injury

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-B and improving mitochondrial function

The short answer is yes and it is one of the most evidence-based strategies available for reducing this harmful type of deep abdominal fat

The ROS reaction and lipidperoxidation induced by free iron can eventuate to ferroptosis and elimination of ATC cells