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SKU: 38684806017

4.6
USD27.50 USD55.50

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Description

Inflammation and apoptosis In the nucleus, Dox can intercalate into DNA and stabilizes topoisomerase II (TOP2)-DNA cleavage complexes, leading to double-stranded DNA breaks (DSBs) and activation of the p53-dependent DNA damage response

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109,110 At cellular interfaces, they build spatially, chemically, and mechanically discrete microdomains

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PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications

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