The plant's effect might also be due to its antioxidant, antiinflammatory, antiobesity, antilipidemic, anti-HC, cardioprotective, antiproliferative, anti-DM, and hepatoprotective properties (526, 527, 532535)
designed PtCu 3 -PEG nanocages, which can serve as horseradish peroxidase-like and GSH peroxidase-like nanozymes for enhanced ROS-based therapy by exhaustion of GSH (Zhong et al., 2020)
GGT transfers the -glutamyl residue of glutathione to amino acid acceptors (the best acceptor being cystine), releasing -glutamyl peptides and cysteinyl glycine
Furthermore, the expansion of pathobionts like Peptostreptococcus can generate detrimental metabolites (e.g., indole derivatives), which directly upregulate cartilage-degrading MMP-13 (2628)
Stay consistent and be patient