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HR = 0.88

According to the above consensus, patients without risk factors may continue their GLP-1RAs therapy in the perioperative period

It is particularly important not to discontinue semaglutide without medical guidance, as abrupt cessation may lead to deterioration in glycemic control or weight regain

doi:10.1016/j.peptides.2019.170230 9

Pre-filled pens for tirzepatide and semaglutide have spent long stretches on the UK shortage list since 2024, and patients are increasingly being prescribed compounded vials by private clinics drawn with an ordinary insulin syringe, not a pen needle