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The first-line approach involves ensuring adequate hydration, as GLP-1 receptor agonists can reduce fluid intake through appetite suppression and may cause mild dehydration, particularly if accompanied by nausea or vomiting

Improved Glycemic Control: In addition to weight loss, tirzepatide helps improve glycemic control by lowering blood sugar levels

In some cases, the dosage may be increased by 25 mg per week until the desired effect is achieved

Understanding this nuanced risk-benefit profile enables informed shared decision-making between healthcare providers and patients considering GLP-1 therapy