The study also found that the likelihood of receiving a first-time diagnosis of T2D or sleep apnea within 15 days of initiating GLP-1 RAs increased with higher overweight/obesity classes
Seek immediate medical attention if tiredness is accompanied by: Symptoms of hypoglycemia : shakiness, sweating, confusion, rapid heartbeat, or dizziness (particularly relevant if you take insulin or sulfonylureas)
In a small-scale four-week long, open-label study involving 14 individuals diagnosed with major depressive disorder and bipolar disorder, which also displayed impaired executive function, treatment with liraglutide significantly reduced Hamilton Depression Rating Scale (HDRS) scores and improved executive function, however, at the same time it did not improve cognitive function in patients [122]
A compounded version is one in which the GLP-1 is mixed with another drug, usually vitamin B12 or L-carnitine, and sold under the scientific name instead of the brand name, he says
In summary, GLP-1RAs reduce ASCVD risk in individuals with T2D, and semaglutide reduces ASCVD in people with obesity, with consistent reductions in MACE observed across multiple CVOTs
