The stigma that sits around these drugs is mainly that they are medication for rich people to look skinny effortlessly, but in the clinic, we are seeing fantastic results: 30-year-old, female, didnt lose baby weight
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Furthermore, because the autonomic nervous system controls digestive motility, this neurological dysfunction loops back to the gut, causing erratic transit times (diarrhea or gastroparesis) that further disrupt the microbiome, locking the patient in a relentless cycle of disease
In the STEP 1 trial extension, participants regained roughly two-thirds of their lost weight in the year after stopping semaglutide, with cardiometabolic improvements largely reverting toward baseline
It can also affect how nutrients and water are absorbed, contributing to loose stools