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*Correspondence: Jun Xu, [email protected] This article was submitted to Endocrinology of Aging, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Isotretinoin is absorbed through the gastrointestinal tract and its bioavailability roughly doubles when taken with a high-fat meal

There is, however, controversy regarding expression of GLP1 receptors (GLP1R) in human normal and diseased thyroid and pancreas

As the study authors pointed out, potential risks to the fetus of using a GLP-1 while pregnant remain unclear, so current recommendations advise discontinuing the drugs prior to or during a pregnancy

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