This is different from oral isotretinoin, which requires a longer waiting period
When to STOP / HOLD Suspected pancreatitis Severe GI intolerance Rapid unexplained weight loss Severe dehydration Before major surgery / procedures where delayed gastric emptying is a concern Practical update: peri-procedural withholding recommendations have evolved over time and can vary by procedure, aspiration risk, and society guidance
Frischmuth T, Hindberg K, Gabrielsen ME, Brumpton B, Hveem K, Braekkan SK, Hansen JB, Morelli VM (2022) Joint effect of multiple prothrombotic genotypes and obesity on the risk of incident venous thromboembolism
The drugs efficacy in treating heart failure with reduced ejection fraction (HFrEF) and its expanding adoption in hypertension management, particularly in China and Japan, contributed to its strong performance
PMID: 29 ZhangHShiHLiXZhouSSongXMaNet al