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n = 3 technical replicates from one experiment

NPI 1417953241 Texas Medical License H1583

Reported side effects in studies include: nausea diarrhea constipation vomiting abdominal discomfort These effects were generally dose-dependent and more common during the early stages of treatment

However, IL-15-mediated upregulation of ZO-1 and ZO-2 expression was independent of the IL-2R subunit, whereas phosphorylation of occludin and enhanced membrane association of claudin-1 and claudin-2 by IL-15 required the presence of the IL-2R subunit

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