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It was developed to mimic the action of naturally occurring MSH, a hormone involved in: Melanin production (skin pigmentation) Immune system modulation Appetite regulation Sexual arousal and libido Inflammatory balance Melanotan II works by binding to melanocortin receptors (MC1R, MC3R, MC4R, and MC5R), which are found not only in the skin but also in the brain, immune system, gut, and sexual organs

Clinical testing of these combination therapies will be necessary to determine whether the effects translate to superior weight loss in obese T2DM patients

(2014) 99:E21016

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