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Dosing : Starting dose is 2.5 mg weekly, increasing every four weeks to a maximum maintenance dose of 15 mg weekly

Should patients with existing AF avoid GLP-1 medications

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Nakamura, N., Davis, K., Yan, J., Sloper, D

Additional evidence that metformin protects mitochondrial function has been provided by Wang et al., reported that treatment of streptozotocin (STZ)-induced diabetic mice with metformin (300 mg/kg/day) in their drinking water for 4 weeks suppressed mitochondrial fission through inhibition of dynamin-related protein (Drp1) via an AMPK-dependent process and enhanced mitochondrial fusion (186)