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Regulation of Blastocyst Migration, Apposition, and Initial Adhesion by a Chemokine, Interferon Gamma-Inducible Protein 10 kDa (IP-10), During Early Gestation
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Geuze, E., et al
day 7: subileus with adhesions ( e )
Following agonist binding, the GLP-1R is rapidly endocytosed, and whilst active G protein coupled receptors (GPCRs) can continue to generate intracellular signals within the endosomal compartment (Eichel and Zastrow, 2018), the availability of surface GLP-1Rs to extracellular ligand appears to be an important determinant of sustained insulinotropic efficacy in a pharmacological setting (Jones et al., 2018b)
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