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Acute behavioural effects of bupropion and naltrexone, alone and in combination, in non-deprived male rats presented with palatable mash This study examined the behavioral effects of bupropion, naltrexone, and their combination on appetite in rats, finding that bupropion disrupted satiety and increased activity, naltrexone accelerated satiety without affecting movement, and their low-dose combination enhanced appetite suppression while reducing bupropions side effects

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