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Redox status and protein binding of plasma homocysteine and other aminothiols in patients with hyperhomocysteinemia due to cobalamin deficiency

Preclinical protocols reported in the literature document typical concentrations of 101000 nM in B16-F10 and MNT-1 melanocyte models for studying the cAMP/PKA/MITF/tyrosinase cascade

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This is an impressive result, allowing these drugs to be considered as more than just "weight loss aids." Research into their potential for treating fatty liver disease, alcohol and nicotine addiction, and even Alzheimer's disease is ongoing

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