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history of or active ischemic, hemorrhagic or anatomical neurovascular disease, including transient ischemic attack, cerebrovascular accident, arteriovenous malformation or brain aneurysm, peripheral vascular disease such as deep vein thrombosis/pulmonary embolism, chronic venous insufficiency, claudication or lymphedema

[PubMed] [Google Scholar] Thal 1996 Thal LJ, Carta A, Clarke WR, Ferris SH, Friedland RP, Petersen RC, et al

Furthermore, BPC 157 inhibits the growth of several tumour lines and can counteract tumour cachexia (Kang et al

Thus, studies conducted on animals have demonstrated that inhibition of the endogenous methylation demand by creatine supplementation can reduce Hcy levels, but these results have not been reproduced in human subjects