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The mechanism of this pharmacodynamic interaction is not known

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Chronic stress combined with hormonal fluctuations creates a metabolic environment where weight loss becomes more difficult

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Store in a refrigerator at 2C to 8C

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Therefore, the GLP-1-induced excitation of MCs, probably via inhibition of voltage-dependent potassium channel conductance and enhancement of glutamatergic neurotransmission, could lead to changed excitability of higher olfactory cortical as well as hypothalamic regions to change metabolic states

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