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In a different communication, we also studied the function of retatrutide in the mouse heart (abstract: Ahlrep et al

CircACC1 is a circRNA derived from the human acetyl-CoA carboxylase 1 ( ACC1 ) gene and directly binds to the and subunits of AMPK, facilitating its activity, 279 and promoting glycolysis and fatty acid -oxidation during metabolic stress

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Cell viability was determined by absorbance, at 595 nm wavelength, with a microplate reader in a SpectraMax M2 (Molecular Devices, Sunnyvale CA)