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Nausea/aversion The concern with nausea resulting from GLP-1 should not come as a surprise as this is in fact the most common side effect reported in patients receiving GLP-1 analog treatment (Calara et al., 1997, 1998

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However, its cosmetic status also means it is not held to the same efficacy-proof standard as an approved drug, and higher-concentration or injectable forms marketed for research use are not approved for human therapeutic use and fall into a legal grey area that varies by jurisdiction