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Hollow microneedles add a fourth mechanism that solid microneedles cannot: the molecule is delivered during channel formation, not after

The following antibodies were used for immunohistochemistry: anti-GPX4 (1:400, Abcam, ab125066), anti-4HNE (1:400, Abcam, ab46545) and anti-MPO (1:200, Dako, IS511) were employed with a secondary biotinylated antibody (Vector, MP-7401)

While some patients report it, it is less typical than recognised effects such as nausea, vomiting or abdominal discomfort

Usharani P, Mateen A, Naidu M, Raju Y, Chandra N