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Decreased self-administration of opioids such as heroin, fentanyl, and oxycodone in rodent models

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10.1016/s0166-2236(03)00162-0 60 KatoT.FunakoshiH.KadoyamaK.NomaS.KanaiM.Ohya-ShimadaW.et al (2012)

We also identified PBH-specific patterns of serotonin dynamics in both the fasting and the postprandial state

To further support the negative impact of meningeal T H 17 immunity on cognitive performance in AD, we assessed the level of T H 17 cells in intestinal-associated tissues of specific-pathogen-free (SPF) relative to germ-free (GF) 5xFAD mice, previously reported to significantly outperform conventional 5xFAD mice in cognitive tests 57