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Side effects are typically mild and may include temporary redness or soreness at the injection site, a brief "flushed" feeling, or short-lived lightheadedness

Key limitation: The intranasal route for bremelanotide was ultimately not pursued for regulatory approval due to the combination of lower and more variable bioavailability, higher incidence of blood pressure elevation, and less predictable pharmacokinetics compared with the subcutaneous route (reported in studies) [10] [17]

Levels typically fall from about 200 ng/mL in young adults to around 80 ng/mL by the time someone reaches 60

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