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Figure 3 3.1 TLR-nuclear factor kappa B signaling pathway As one of the earliest identified PRR families, TLRs comprise 10 members in humans (TLR1-10) and 12 in mice (TLR1-9, 11-13) ( Simultaneously, the IRAK-TRAF6 complex activates mitogen-activated protein kinase kinase (MKK) cascades, thus leading to activation of activator protein 1 (AP-1), which is another critical transcription factor in inflammation ( Figure 4 )

QUICK FACTS Quick Facts Boiga melanota Scientific Name: Boiga melanota Common Name: Malaysia Mangrove Snake(although also found in Thailand and Indonesia) Origin: Southeast Asia Size: ~58 feet (varies) Behavior: Arboreal, nocturnal, highly alert Diet: Lizards, birds, small mammals, amphibians NATURAL HISTORY Boiga melantoa is one of the largest, if not THE largest Boiga if you take into consideration overall size and mass