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While phytochemical effects on incretin pathways are mainly supported by metabolic and diabetes studies, and incretin-mediated neuroprotection in PD is well-documented, combining these findings provides a strong rationale for exploring plant-derived compounds as adjunctive neuroprotective strategies in PD ( Table 1 represents the current and emerging drug candidates and their molecular targets in PD

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Cycle timing

Role of GluR2 in Synaptic Plasticity Long-term depression (LTD) in the cerebellum is a type of synaptic plasticity and one of the most critical mechanisms for motor learning [24,25,26,27]