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discontinue immediately and seek medical attention if you experience severe abdominal pain

It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2

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Schistosoma , P28 glutathione-S-transferase (P28GST), combines the activities of antioxidant glutathione S-transferase and prostaglandin D synthase [115,116]

Chen F, Wang W, Ding H, Yang Q, Dong Q, Cui M