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References Mller TD, Finan B, Bloom SR, et al

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Common Side Effects Nausea Vomiting Diarrhea Stomach pain Decreased appetite Serious Side Effects Pancreatitis (severe stomach pain, nausea) Gallbladder issues (gallstones, pain in the upper abdomen) Thyroid tumors (seen in animal studies) Some patients also report feeling still hungry on semaglutide, which may be related to how their body responds to the medicationor differences in dosage or absorption

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Standard TRT alone suppresses natural testosterone production via the hypothalamic-pituitary-gonadal axis, reducing luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which leads to decreased sperm production and potential infertility