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As a peptide, BPC-157 also carries a theoretical potential for immunogenicity (antibody formation) with repeated dosing, which has not been studied longitudinally in dogs
Strong candidates are adults with specific clinical situations where peptide therapy has a reasonable mechanistic rationale and clinical experience: soft-tissue injury recovery for BPC-157, age-related decline in GH-related markers for growth hormone secretagogues, targeted skin or tissue applications for GHK-Cu
With internal fistulas in the colon and the bladder, with BPC 157 therapy, the colon and bladder defects showed simultaneous healing effects, including closing of the colovesical fistula in a matching healing process ( c ) and a normal voiding in BPC 157-rats ( b )
Deamidation occurs when asparagine and glutamine residues lose their amide groups, converting to aspartic and glutamic acid respectively
