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A comprehensive search of Web of Science, Embase, and PubMed was conducted to identify observational studies that assessed the association between e-cigarette use and the risk of COPD, providing risk estimates (hazard ratios, risk ratios, or odds ratios) for current, former, and ever e-cigarette users

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All thirteen had a free hand to realize their horrible visions in separate one-hour film and the result is among the most nasty ever seen