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Lancet 376:595605 Apovian CM, Aronne L, Rubino D et al (2013) A randomized, phase 3 trial of Naltrexone sr/bupropion SR on weight and obesity-related risk factors (COR-II)

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Concurrently, it enhances the efficiency of the immune system, improving surveillance mechanisms that can eliminate residual tumor cells or micrometastases, thereby reducing the risk of recurrence (42)