In 2004, electronic cigarettes (EC) were introduced to the market as a healthier alternative for chronic smokers dependent on nicotine, allowing them to smoke without the risks of tar and other toxic tobacco compounds (5)
It is illegal to sell cigarettes in a smaller quantity than that placed in the pack or other container by the manufacturer is prohibited
Some cigarillos are made with a replacement wrapper, as opposed to pure tobacco leaf
The purpose of this act was to regulate the manufacturing, importation, wholesale, distribution, and retail sale of tobacco products, while generating revenue through excise taxes on these products
To overcome these limitations, we developed a whole CS extract (WCSE) model that combines both particulate and gaseous components to more accurately represent the physiological complexity of a chronic exposure platform