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Male Sprague-Dawley rats were exposed daily to the smoke of two 1R1 reference cigarettes, beginning on day 1 after birth and continuing for 5, 10, or 20 days

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Researchers found significant, reciprocal associations between [e-cigarette] and cigarette use. The data show that more frequent e-cigarette use at one point in time during the study predicted more frequent cigarette use at a later time during the study, and vice versa

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