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5.3.3 Ferroptosis in coronary microvascular dysfunction Coronary microvascular dysfunction, a distinct pathological entity within the spectrum of coronary heart disease, involves significant ferroptotic endothelial cell death

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Furthermore, the recent study suggests that selectively inhibiting glutamine metabolism in tumor cells can alleviate the competitive glutamine stress within the TME, thereby making more glutamine available to immune cells and promoting anti-tumor immunity [132]

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The results obtained also show a further increase in glutathione peroxidase activity in the magnesium and insulin treated diabetic groups suggesting a potentiating effect of magnesium on the activity of this enzyme in these treatment groups (Table 2)