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Current regulatory frameworks for tobacco and nicotine-containing products (TNCPs) are strongly emphasizing standardized, high-throughput in vitro models with toxicologically relevant endpoints 16

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Centers for Disease Control and Prevention, USA Northern Ireland Statistics and Research Agency (2017) Northern Ireland Multiple Deprivation Measure 2017 (NIMDM2017)

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Cigarette smoking has a direct negative impact on general health and also harms fitness level