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Trends Cancer 6 , 838857 (2020)

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A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data

Clinical evidence supports PRP increasing hair density in androgenetic alopecia, in both men and women

While mechanistically interesting, stacking three or more compounds dramatically increases complexity, cost, and potential for unexpected interactions