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It is used to help stabilize other ingredients and create a thicker gel-like texture

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Some people may experience mild digestive changes when starting a new supplement, but these typically resolve quickly

We also explored several other known regulators of PGC1 activity that are altered in response to 5FU treatment in HCT116, including NRF2, reactive oxygen species and PPAR, but none of these prevented PGC1-driven increases in mitochondrial mass

doi: 10.3389/fonc.2025.1700439 Received 11 September 2025 Accepted 27 October 2025 Published 17 November 2025 Volume 15 - 2025 Edited by Zodwa Dlamini, Pan African Cancer Research Institute (PACRI), South Africa Reviewed by Yuan Qin, Xijing Hospital, The Air Force Medical University, China Hong Sun, Fudan University, China Updates Copyright 2025 Ao, Liu, Yin and Zhao