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Diabetes Care 42(9):17241732 Aroda VR, et al (2023) Efficacy and safety of once-daily oral semaglutide 25 mg and 50 mg compared with 14 mg in adults with type 2 diabetes (PIONEER PLUS): a multicentre, randomised, phase 3b trial

It is noteworthy that SP is also efficient in directly inhibiting RANKL-induced osteoclast differentiation, which plays a synergistic role in remodeling bone homeostasis in RA (Fig

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