Adding to the competitive landscape, Kailera Therapeutics and Hengrui Pharma reported positive topline data from a Phase 2 study of oral ribupatide, a GLP-1/GIP dual agonist, showing approximately 12% mean weight loss at 26 weeks compared to 2.3% for placebo
were supported by the grants from the Cancer Prevention and Research Institute of Texas (RP220032, RP150551, and 632 RP190561) and the Welch Foundation (AU-0042-20030616)
Individual responses vary based on lifestyle habits, metabolism, and starting weight
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
We also appreciate Judith Kimble and Sarah Crittenden for making the GLP-1::V5 CRISPR/Cas9 strain available prior to publication, for the kind gift of sdn-1 Minimos rescue constructs by Hannes Bulow and Dayse S